https://www.wythelab.com/frogandfish-club daily 0.75 2016-02-15 https://www.wythelab.com/frogandfish-club/2016/2/19/25ul7bk1yh7sdh42pfkuzk7ng0t1ub monthly 0.5 2016-02-15 https://www.wythelab.com/frogandfish-club/2015/12/11/frog-and-fish-club monthly 0.5 2016-02-08 https://www.wythelab.com/frogandfish-club/2015/11/20/a2ncku0wyb3ox9l0aa7xzh4mjzgy7r monthly 0.5 2016-02-08 https://www.wythelab.com/frogandfish-club/2016/1/22/frog-and-fish-club monthly 0.5 2016-02-08 https://www.wythelab.com/frogandfish-club/2015/4/17/tmc-frogfish-club-meeting monthly 0.5 2014-10-16 https://www.wythelab.com/frogandfish-club/2015/3/20/tmc-frogfish-club monthly 0.5 2015-01-16 https://www.wythelab.com/frogandfish-club/2015/2/20/tmc-frogfish-club-meeting monthly 0.5 2015-01-16 https://www.wythelab.com/frogandfish-club/2015/1/23/tmc-frogfish-club-meeting monthly 0.5 2015-01-16 https://www.wythelab.com/frogandfish-club/2014/12/19/tmc-frogfish-club-meeting monthly 0.5 2014-11-07 https://www.wythelab.com/frogandfish-club/2014/11/21/tmc-frogfish-club-meeting monthly 0.5 2014-11-20 https://www.wythelab.com/frogandfish-club/2014/10/17/frogfish-club-meeting monthly 0.5 2014-10-16 https://www.wythelab.com/etc-links daily 0.75 2014-10-02 https://www.wythelab.com/home daily 0.75 2020-10-27 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1591044382157-YTOATKHFE1WZW52EQSAR/Pride_BLM-01.png Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1591044382157-YTOATKHFE1WZW52EQSAR/Pride_BLM-01.png Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1533134952324-2KKC3DNIGAZ4XSBTBQ13/Mouse_Adult_Brain_uCT_Coronal.png Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1533135262166-E2POVGBER0N1LWC7K9EB/uCT_Adult_Mouse_Brain_Coronal.jpg Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1533135003026-ZCZATF4GI341UWFNVJSZ/Picture3.png Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1453497962310-YYYRM1THP2O35JJQ6QD0/TP1-venus_kdrl-mCherry.jpg Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1440521486560-TVT42VAY9TLS3VQI084B/image-asset.jpeg Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1462488272711-HP2J48FUCZVMWQYY60PT/Retina_Apj_CreER.jpg Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521061851231-S2XWVZDBI6SI9XZ7R3SU/Picture1.png Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1494716964255-8LXACQPWXZN929R5QKHK/Retina_2.jpg Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1464817089638-OTWASZKGSSUQGQDV3VA6/2016-05-26+ERG+H0172+F+WT+10_Maximum+intensity+projection5_whole+mount_MIP_stiched-SCALE.jpg Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1494702700185-PLRMHW8CSZ0I2O3GR3BY/05_13_2017_coalign_SKIN.jpg Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1591044825293-1N0A6UVYTTCFFE9TPA27/Pride_BLM-01.png Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1453496765581-3OKEXH3787X9U66IEX1E/IMG_2540.jpg Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521064669483-PC77USRZHWMLC07TZUVD/Picture3.png Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1439576943597-EZFYMWWS9F9OMPY4IZK2/F2GFPbrain.png Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521061775809-TD8R3COB57HPEXV9OWJ0/Picture1.png Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1444151056400-5QSUBBLHMHRNHOCGNF5I/2015-09-24+E9_Maximum+intensity+projection.5_PECAM_Tuj1_1_Merge_scale.jpg Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1412178918466-Q6QUKOC2KGQHSE8UA6I0/PECAM+E9-5.jpg Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1412115446116-WP8JOROAMG5U9955M67T/Dll4+BAC+nLacZ+4336+E9-5+0004.jpg Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1453496772897-U7PP01UZXYB1A9RRQTRO/IMG_2538.jpg Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1412181952873-0BYBE5YJ2WIBT7IG92AX/Brain+h2B+PECAM+10.5.jpg Home The cranial vasculature of an E10.5 mouse embryo with all vessels labelled in red by IHC for CD31/PECAM, and the arteries labelled by IHC for GFP (Dll4-F2-hsp68::H2B-EGFP). https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1414017021937-IM00ZRP3PQ1PFJHEN19I/E10-5+Brain+zoom.jpg Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1414095243467-6F8PEES4K6IJ83Q42VOT/image-asset.jpeg Home - An E14.5 Tbx5-CreER/+; R26mTmG/+ heart pulsed at E7.5 with Tamoxifen. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1433006235404-BX7IZEZ8F1O1YHVBDVP4/2015-05-21+E10p5_4_AF_CD31_SMA_001.jpg Home - E10.5 mouse embryo stained with CD31 (green) and SMA (magenta) imaged by lightsheet microscopy https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1412177854301-0LA19EUPDP0FXLP9Q1UJ/Cdh5cre+adult+Retina.jpg Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1412612855270-E23CKI5KJI23IET89229/TP1-RFP+ETV2-GFP+30-36+hpf.jpg Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521061785026-J5CPK7TGM6VRQSOA9ATV/Brain.png Home https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1549384428550-S12RFV9H2OM5GYM7YDDA/IMG_7362.jpg Home https://www.wythelab.com/people-1 daily 0.75 2026-02-16 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1761931936011-Y57RQ55OYPBIJLAPXP6I/Halloween_2025.JPG Group Photos https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1761931936011-Y57RQ55OYPBIJLAPXP6I/Halloween_2025.JPG Group Photos https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1761932524696-4ASU641E4659Q1ZCS52X/Lunch_Summer_2025.jpg Group Photos https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1749694611816-TM8ZX03D7CXBWKF0PVKK/image1.jpeg Group Photos UVA faculty represented well at NAVBO 2024! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1649360980517-44Q0S4KSXIDA7CVAL92U/MicrosoftTeams-image+%282%29.png Group Photos https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1721249283102-EG9VIYNPA4P9F9QQDET3/DevilsBackbone_June_2024.jpg Group Photos A little happy hour action at Devils Backbone Backyard to celebrate Omar's last day and Jacob's joining the lab. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1659543814804-K56ZL4DLDT1FYJDW6JIV/IMG_3348.jpeg Group Photos - Lab dinner at Armadillo Palace, Summer 2022. Great team! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1649361045836-D2OEOLAXXA0T56JFGU1J/MicrosoftTeams-image+%281%29.png Group Photos - After the 2022 CVRI symposium, looking fancy! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1643495960782-9SX6PD4D10GFWOLNR9IE/IMG_9100.JPG Group Photos - Lab dinner at Hu's Cooking! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1648576175883-DDLL5MB4IB07ET63ZKTX/Armadillo_Palace_2022.png Group Photos https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1564436872513-00K071EEUL4AW0DHYTRU/IMG_7207+2.jpeg Group Photos Getting burgers together out at Hop Doddy in Rice Village, summer 2019. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1573162202821-JTHRPZS6K4SZX0TB880K/IMG_9099.JPG Group Photos Lab dinner at Hu’s Cooking to celebrate Meng, Alex, and Andrew joining the team and Jiao’s rotation! October, 2019. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1478818055966-LETSOHR99FXZGMGZFYEW/Ctj9FG3VYAEymmS.jpg Group Photos The team cranking away in the lab! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1535574460181-REB8UZIU6I3YT1QKJD1S/32709151_2099885273633954_1445678299547172864_o.jpg Group Photos Manuel walking folks through his poster at the annual CVRI symposium in 2017 at BCM. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1535574003697-ZGB4Z047XT1FM0T8QD3N/Image-3.jpg Group Photos Lab dinner at Hop Doddy to wish Abiud well back at college and to celebrate Carlos joining the lab. Alex Herman was missed! Summer 2018. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1466092960179-7URNET7I0UI44WSH56I1/IMG_2990.JPG Group Photos Taco Friday at "Many's taco truck" with the entire lab. (L-R) Manuel, Kesha, Alex, Karen, and Josh. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1573163133745-CMV4BUWMGYCSTZ56OKX8/EExKF85XkAQi1bZ.jpg Group Photos Giving a talk at the Smithville Campus of MD Anderson Cancer Center. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1478818124954-1950R9HJ3SG11OIL0N4G/Cu02-oJVMAABAS_.jpg Group Photos Giving a talk at the South West Regional SDB meeting at Salt Lake City, October, 2016. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1478818062022-IKLT15716FD9K8SW47A8/Cth7LmiVYAEk-X7.jpg Group Photos Manipulating embryos with my former graduate school classmate, George T. Eisenhoffer, in his lab across the street at MD Anderson Cancer Center. Go fish! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1453524923410-6UF0R2UEE92LCO00G3G4/CQZgtfKUkAALtIH.png Group Photos Giving a talk at the 2015 Southwest Society for Developmental Biology Regional Meeting. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1453496401115-GT6RCJD9Y1TIX269LY3Y/IMG_2588.jpg Group Photos Lab lunch at Torchy's Tacos! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1573162293292-S4B3ZO78WDATHT1Z8J7F/r_1-Group-Photo-2019-Scientific-Conference_cropped.jpg Group Photos 13th Cure HHT International Scientific Conference Photo. Josh is in there somewhere! An awesome meeting in Puerto Rico! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1573162391713-DK6WEVGQG9KLQABO8SNK/DLfl6P3UEAALU_3.jpg Group Photos A whole lotta University of Utah Alumni in one room at the Southwest Society for Developmental Biology 2017 meeting poster session. Houston did a great job hosting this awesome regional meeting! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1453496401204-MXPH4JGOIRD14NRNN3TT/IMG_1768.jpg Group Photos Holiday Lights in Houston. They look remarkably like vessels! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1573163382004-MOZO7632BHJ5TB62Q2NU/D6SdDcdWAAI6Bax.jpg Group Photos Talking at the 2019 Weinstein Cardiovascular Development and Regeneration Meeting in Indianapolis. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1481804613347-U8LCHQ1EXPHSX1HX0Q5T/Wythe+Lab+Christmas.png Group Photos https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1453496394851-2EH2VD0ZP0BTBT7EZKMN/IMG_610_jpg.jpg Group Photos Alex wins a blue ray player at the holiday raffle. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1549384385341-4BQ4YDJ17M123ELC1UPV/IMG_1403.JPG Group Photos https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1643495905083-9TLWOH7M1K06728STBDB/FGhzNRbWUAAaesJ.jpg Group Photos - Celebrating Manuel's defense! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1643495914695-4HDG11ME9HLV3EASCPUS/FGhzNRcXoAEqQ5l.jpg Group Photos - Manuel's thesis defense cake! Gabrielle's got some hidden talents! https://www.wythelab.com/people2 daily 0.75 2026-02-23 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1453524684255-0DG6ZBZGCA67FCDN47K0/image-asset.jpeg WytheLabPeople Principal Investigator Joshua Wythe, PhD https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1453524684255-0DG6ZBZGCA67FCDN47K0/image-asset.jpeg WytheLabPeople Principal Investigator Joshua Wythe, PhD https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1657817052827-W42JGICWAA6LLZGQU6AD/Oscar_Ruiz.jpg WytheLabPeople Staff Scientist Oscar E. Ruiz, Ph.D. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1749692599955-I1T8XV4NAV6ANCHBQOVF/download.jpg WytheLabPeople Research Scientist Azeez Olakunle Ishola, Ph.D. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1603743924389-CIFCJOEXUEM7X991MTUD/thumbnail_Largoza_Image_1.jpg WytheLabPeople Graduate Student Gabrielle Largoza, B.S. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1750105973979-TSR0JN3LAZJT116LFME1/2015-09-24+E9_Maximum+intensity+projection.5_PECAM_Tuj1_1_Merge_scale.jpg WytheLabPeople Graduate Student Kandace Monique Moore, B.Sc. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1738254349747-WD68I7OJR0ZDEXDU69OG/IMG_6382.jpg WytheLabPeople Lab Specialist Athira Pillai, B.Sc., M.Sc. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1690287206109-1QXHOLSQCDNE5V6W5VOC/IMG_7746.jpeg WytheLabPeople Research Technician II William Gillespie, B.Sc. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1738255656649-W72UOZE1FZYVHXAWPVAI/1657492496203.jpg WytheLabPeople Research Technician Natalie Lisenby, B.Sc. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1648575527697-V3JN05KMG56PPOPUJC0P/Picture1.png WytheLabPeople Project Intern / MS3 at BCM Ashley Ricciardelli, B.Sc. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1749691967105-NAWEEVH5QEE726REQO8E/pET+Vector%5BpET+Vector-ALL%5D.jpg WytheLabPeople Lab Specialist Jaden Singh, B.Sc. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1749695109678-RJUZBSJNVNMQDIE6YOSE/Cdh5cre+adult+Retina.jpg WytheLabPeople UVA Cancer Center STRIVE Scholar Mengistu Shukare, PhD https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1714961500237-9AVDWTMZF2SVPXD6SMGL/image+1.jpg WytheLabPeople Undergraduate Researcher Parker Chapman https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1715785538054-YA029XBWZNTU8IMQ9UHX/651+A+mTmG+R%26G2.jpg WytheLabPeople Undergraduate Researcher Michelle Sherman https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1715351894739-YIUJMUZ7FHIO20I3N6AU/2015-05-21+E10p5_4_AF_CD31_SMA_001.jpg WytheLabPeople Undergraduate Research Lili Mosser https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1749692357559-E65QUYP4W917W4M4XVSK/Brenda+Lab+Bio+Pic+-+Color.jpg WytheLabPeople Undergraduate Research Brenda Lu https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1750106873528-R2P9TBK7NVZVMP5B72ZR/Lin_Karen_Photo.jpg WytheLabPeople Undergraduate Researcher Karen Lin https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1750264761814-J6BID5ZVN1E9CDFITOLP/IMG_2850+%281%29+%281%29.jpeg WytheLabPeople Undergraduate Researcher Anika Singh https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1738256014411-LFZSJVMYFVJ2J8RD62DM/pET+Vector%5BpET+Vector-ALL%5D.jpg WytheLabPeople Undergraduate Researcher Ebtesaam Lamya Abdul-Qudoos, https://static1.squarespace.com/static/542b27b6e4b04193388466d4/5996e848f7e0aba05650503e/684a3e1d4833f37fee6ea0f5/1763670070795/ WytheLabPeople Undergraduate Researcher Karen Lin https://www.wythelab.com/home-1 daily 1.0 2024-08-03 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1603985404722-TEJRKAW1M0D1LG72KTM9/IB4%2BBrain%2BWhole.jpg HOME https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1603998281994-8SWOP0PBKTE3GZR0DNAQ/KRAS_bAVM.jpg HOME https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1603999108150-RIP98JGNCF5EQDMSZS5L/2015-05-21+E10p5_4_AF_CD31_SMA_001.jpg HOME https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1604003260172-OT054LY28SSM3J5BQCY4/IMG_1273.JPG HOME 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https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1604028107168-6FZKV67CW68RU5OY86XV/D6SdDcdWAAI6Bax.jpg HOME https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1604003603505-XM4WQ430O35JDQWG5Z7C/IMG_7207.jpeg HOME https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/05d73da0-1202-459e-a5cb-f4720de98da6/MicrosoftTeams-image.png HOME - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1604004112961-EO3PH8JTAESYNJ08ME77/Cure_HHT_2019.jpg HOME https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/e389c59f-a2ea-400e-9404-e3b63c2257da/FGhzNRbWUAAaesJ.jpg HOME - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.wythelab.com/ssrsandlineagetracing-1-1-1 daily 0.75 2015-02-08 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1423405748221-XQFYU0URTE0WJZZEXUHK/Cre+diagram.png SSRs and Lineage Tracing 4 https://www.wythelab.com/heart-development daily 0.75 2021-01-19 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1413847791392-MJWF5O80I89S2K9IVLNV/Figure+4.jpg Heart Development - Tbx5-CreER; R26-lacZ cells labeled at E6.5 and observed at E10.5 contribute to left ventricle and atria. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1413847677783-RV6QANLM5IYGLM5788A0/Figure+4.jpg Heart Development - Tbx5+ cells labeled at E7.5 and observed at E14.5 for mTmG, whole mount on the left, vibratome section on the right. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1413846901453-3NMUGS9VQQBL1IEUFS5G/Image+693.jpg Heart Development - Frozen sections of a E14.5 Tbx5-CreER/+; R26-EYFP heart pulsed at E6.5 and stained with CD31 (red), DAPI (blue), and GFP (green) https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1414094894105-9OTFKFAZQS78G2KPKBM0/Apex+R%26G.jpg Heart Development - A confocal stack of the septum of an E14.5 Tbx5-CreER/+; R26-mTmG/+ heart pulsed at E7.5 with tamoxifen. https://www.wythelab.com/aquaticlabsattmc daily 0.75 2014-10-28 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1413741153526-VCDBWIG3IC37YPJIY835/image-asset.jpeg Aquatic Labs at TMC https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1413746382212-AUPPHNK73KUJV4SPZGB9/frog_close.jpg Aquatic Labs at TMC https://www.wythelab.com/cardiac-lineage-maps daily 0.75 2023-11-01 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1414115737508-6ZDEYGCG5LCY8S8EL3JL/image-asset.jpeg Cardiac Lineage Maps https://www.wythelab.com/ssrsandlineagetracing-1-1 daily 0.75 2015-01-31 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1422019579160-BGY4KPQCTAXQSBFV05CO/Dre+Rox+Model+1.jpg SSRs and Lineage Tracing 3 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1423405590540-AOY0XT3TGK5AT9TQEUP6/Slide3.jpg SSRs and Lineage Tracing 3 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1422019637514-VHGXC3HHYAR7QA4HP5ID/Dre+Rox+Model+2.jpg SSRs and Lineage Tracing 3 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1423405865309-GIOE2Y4S8XUCP0FI1TWM/Slide4.jpg SSRs and Lineage Tracing 3 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1422019689370-RVVJE0KXH586B3QF9DGJ/Mef2c-DRE+nKmB.jpg SSRs and Lineage Tracing 3 https://www.wythelab.com/ssrsandlineagetracing-1-1-1-1 daily 0.75 2015-02-08 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1423405791522-PQV6U2WBXO1E5IOG2C4T/Cre+diagram.png SSRs and Lineage Tracing 5 https://www.wythelab.com/tmc-frogfish-group daily 0.75 2019-12-13 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1413739429480-CHAPAZB9JE08DSE715L8/Control05.jpg TMC Frog/Fish Group - Two-color dye injection into the eyes of a 96 hpf zebrafish embryo to visualize crossing of the optic chiasm. Image courtesy of the Wythe Lab. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1413750140569-MTMXRYW2S7WULFBHGAN4/Hadp1+KV.jpg TMC Frog/Fish Group - IHC aPKC (red) and acetylated tubulin (green) for visualization of ephithelium and cilia in Kupffer's Vesicle of a 12-16 somite stage zebrafish embryo. Image courtesy of the Amack and Wythe Labs. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1413750108495-5C10ZQA3CPGUU8XT7MZD/TP1-RFP+ETV2-GFP+30-36+hpf.jpg TMC Frog/Fish Group - TP1::nls-mCherry (active Notch signaling); ETV2-BAC::eyfp (endothelium) 36 hpf zebrafish embryo. Image courtesy of the Wythe lab. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1413739385203-NAD825WDTR25JLXBAAX5/48+hpf+fish+head.jpg TMC Frog/Fish Group - Tg(Dll4-F2-E1b::EGFP) (arteries); Tg(kdrl::mem-mCherry) (all endothelium) zebrafish embryo, dorsal view. Image courtesy of the Fish and Wythe Labs. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1576253617086-PY814Y80EID5N5CTL8QT/AquaticModelsSeminar_Fall2019Spring2020.jpg TMC Frog/Fish Group https://www.wythelab.com/dre-rox daily 0.75 2014-10-23 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1414097665605-1RXX83RVCREDN4UQUJGV/Dre+Rox+Model.jpg Dre Rox https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1414097715185-GCOOHOP1S98F9JULENWA/Dre+Rox+Model+2.jpg Dre Rox https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1414099879594-VTFA4LAOM9C3COZ65L5M/Mef2c-DRE+nKmB.jpg Dre Rox https://www.wythelab.com/targatt daily 0.75 2015-12-11 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1415135509304-3ND8Q5FJCW8VR9YBXNZF/MouseHowitworks.png TARGATT https://www.wythelab.com/endothelial-lineages daily 0.75 2023-11-01 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1415725879709-4XU5P8XLKQ3GYHAD3OE6/Tie2+Cre+Various+Activity.jpg Endothelial Lineages https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1473955855091-Y27MDG5KPWGDV3DZM91B/image-asset.png Endothelial Lineages https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1473956829817-3PAZK7RTTRIEYOPBFK5N/image-asset.png Endothelial Lineages https://www.wythelab.com/cardiovascular-pathologies daily 0.75 2023-07-25 https://www.wythelab.com/septation daily 0.75 2021-01-19 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1414096761107-QFPUVUE5QXQQ4RAYMXNL/Septation+Model+0.jpg Septation https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1414096789201-AJHH0WSBPY3KDI3TPR12/Septation+Model+1.jpg Septation https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1414096812435-3LH0A4DXYGGN8JNP44M4/Septation+Model+2.jpg Septation https://www.wythelab.com/ssrsandlineagetracing daily 0.75 2020-11-04 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1423404819999-7GA5CSE6FLITWE6RXQPF/Cre+diagram.png SSRs and Lineage Tracing https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1422714717645-4DXD987KW75TIYKIM1X7/image-asset.jpeg SSRs and Lineage Tracing from http://www.tcichemicals.com/eshop/en/us/category_index/00317/ https://www.wythelab.com/ssrsandlineagetracing-1 daily 0.75 2020-11-04 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1423404862337-IATWF2QWER0A0WBKJ0RY/Cre+diagram.png SSRs and Lineage Tracing 2 https://www.wythelab.com/zebrafish-protocols daily 0.75 2023-11-01 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1698851750304-0S4GHBUA2ZQF77AFMIIJ/IMG_7362.jpg zebrafish protocols https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/8fce9e5f-0218-49a5-9ac4-c6ea44ebb416/IMG_7361.jpg zebrafish protocols - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.wythelab.com/joshuawythe daily 0.75 2024-07-11 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1420464130511-ZE0Q90XCZ63JHGR8GTDK/image-asset.jpeg joshwythe https://www.wythelab.com/protocols daily 0.75 2023-11-01 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1698852113651-MYQFOB2CCMO1XIQWLH3W/Retina_Apj_CreER.jpg Protocols https://www.wythelab.com/news daily 0.75 2014-10-08 https://www.wythelab.com/seminars daily 0.75 2014-11-12 https://www.wythelab.com/blogspace daily 0.75 2022-01-27 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1415195102393-81EGYXIMBXWK8QRAIUIN/image-asset.jpeg Blogs https://www.wythelab.com/people daily 0.75 2020-10-27 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1761931936011-Y57RQ55OYPBIJLAPXP6I/Halloween_2025.JPG People https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1761932524696-4ASU641E4659Q1ZCS52X/Lunch_Summer_2025.jpg People https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1749694611816-TM8ZX03D7CXBWKF0PVKK/image1.jpeg People UVA faculty represented well at NAVBO 2024! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1721249283102-EG9VIYNPA4P9F9QQDET3/DevilsBackbone_June_2024.jpg People A little happy hour action at Devils Backbone Backyard to celebrate Omar's last day and Jacob's joining the lab. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1659543814804-K56ZL4DLDT1FYJDW6JIV/IMG_3348.jpeg People - Lab dinner at Armadillo Palace, Summer 2022. Great team! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1649361045836-D2OEOLAXXA0T56JFGU1J/MicrosoftTeams-image+%281%29.png People - After the 2022 CVRI symposium, looking fancy! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1643495960782-9SX6PD4D10GFWOLNR9IE/IMG_9100.JPG People - Lab dinner at Hu's Cooking! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1648576175883-DDLL5MB4IB07ET63ZKTX/Armadillo_Palace_2022.png People https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1564436872513-00K071EEUL4AW0DHYTRU/IMG_7207+2.jpeg People Getting burgers together out at Hop Doddy in Rice Village, summer 2019. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1478818055966-LETSOHR99FXZGMGZFYEW/Ctj9FG3VYAEymmS.jpg People The team cranking away in the lab! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1535574460181-REB8UZIU6I3YT1QKJD1S/32709151_2099885273633954_1445678299547172864_o.jpg People Manuel walking folks through his poster at the annual CVRI symposium in 2017 at BCM. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1535574003697-ZGB4Z047XT1FM0T8QD3N/Image-3.jpg People Lab dinner at Hop Doddy to wish Abiud well back at college and to celebrate Carlos joining the lab. Alex Herman was missed! Summer 2018. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1466092960179-7URNET7I0UI44WSH56I1/IMG_2990.JPG People Taco Friday at "Many's taco truck" with the entire lab. (L-R) Manuel, Kesha, Alex, Karen, and Josh. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1573163133745-CMV4BUWMGYCSTZ56OKX8/EExKF85XkAQi1bZ.jpg People Giving a talk at the Smithville Campus of MD Anderson Cancer Center. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1478818124954-1950R9HJ3SG11OIL0N4G/Cu02-oJVMAABAS_.jpg People Giving a talk at the South West Regional SDB meeting at Salt Lake City, October, 2016. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1478818062022-IKLT15716FD9K8SW47A8/Cth7LmiVYAEk-X7.jpg People Manipulating embryos with my former graduate school classmate, George T. Eisenhoffer, in his lab across the street at MD Anderson Cancer Center. Go fish! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1453524923410-6UF0R2UEE92LCO00G3G4/CQZgtfKUkAALtIH.png People Giving a talk at the 2015 Southwest Society for Developmental Biology Regional Meeting. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1453496401115-GT6RCJD9Y1TIX269LY3Y/IMG_2588.jpg People Lab lunch at Torchy's Tacos! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1573162293292-S4B3ZO78WDATHT1Z8J7F/r_1-Group-Photo-2019-Scientific-Conference_cropped.jpg People 13th Cure HHT International Scientific Conference Photo. Josh is in there somewhere! An awesome meeting in Puerto Rico! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1573162391713-DK6WEVGQG9KLQABO8SNK/DLfl6P3UEAALU_3.jpg People A whole lotta University of Utah Alumni in one room at the Southwest Society for Developmental Biology 2017 meeting poster session. Houston did a great job hosting this awesome regional meeting! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1453496401204-MXPH4JGOIRD14NRNN3TT/IMG_1768.jpg People Holiday Lights in Houston. They look remarkably like vessels! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1573163382004-MOZO7632BHJ5TB62Q2NU/D6SdDcdWAAI6Bax.jpg People Talking at the 2019 Weinstein Cardiovascular Development and Regeneration Meeting in Indianapolis. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1481804613347-U8LCHQ1EXPHSX1HX0Q5T/Wythe+Lab+Christmas.png People https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1453496394851-2EH2VD0ZP0BTBT7EZKMN/IMG_610_jpg.jpg People Alex wins a blue ray player at the holiday raffle. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1549384385341-4BQ4YDJ17M123ELC1UPV/IMG_1403.JPG People https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1643495905083-9TLWOH7M1K06728STBDB/FGhzNRbWUAAaesJ.jpg People - Celebrating Manuel's defense! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1643495914695-4HDG11ME9HLV3EASCPUS/FGhzNRcXoAEqQ5l.jpg People - Manuel's thesis defense cake! Gabrielle's got some hidden talents! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1415121018625-GJEC681ORVSD4515FWTQ/image-asset.png People https://www.wythelab.com/researchoverview daily 0.75 2025-10-31 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1604065351023-HL79HXV006C8SUKI4LYM/unspecified.jpg PROJECTS https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/b19be871-6127-4741-843a-794fcbf8357d/E8XNZrmXIA8yXWE.jpg PROJECTS - Make it stand out Images displaying the heterogeneity in patterning of the adult vasculature from a mouse perfused with fluorescent lectin. https://www.wythelab.com/contact-us daily 0.75 2025-01-30 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1603989548639-X3NX9FNOYCVI0VFYEZW7/Figure%2B4.jpg CONTACT https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/c138be88-9040-4658-8332-593ec0acd54b/201904-sunset.jpg CONTACT https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/8ba505f0-1649-40d7-a894-829f095ac250/uva_som_large.png CONTACT https://www.wythelab.com/employment daily 0.75 2021-06-09 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1412531259579-461HHTKV184MJDM1359M/image-asset.png Employment https://www.wythelab.com/etc daily 0.75 2025-11-21 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1604176393129-468V1H3O2E5E1MQV30GS/Dll4-BAC%2BE15.5%2Bcopy.jpg LINKS https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1534214715424-S0PZ9EZ58Z37KPMDY0E3/10_31_16_Vegfr2_notch.jpg LINKS E10.5 CBF::H2B-Venus (Notch Reporter); Vegfr2::myr-mCherry mouse embryo. https://www.wythelab.com/factsandfigures daily 0.75 2015-08-20 https://www.wythelab.com/mouse-genotyping daily 0.75 2023-11-01 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1698852030672-5S67JBOFUJTRC6C7NUG8/Untitled%2B1.jpg Mouse genotyping https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1412790312013-44XWB6WOGG7RLFJIX5S1/A-laboratory-mouse-6332313.jpg Mouse genotyping https://www.wythelab.com/protocols-1 daily 0.75 2023-11-01 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1698851949410-XQB0VFJRBIMX6WM5V2RB/Murine_Retina_SMA.jpg Mouse Protocols https://www.wythelab.com/congenital-cardiac-defects daily 0.75 2021-01-19 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1423408115966-RHG68KSQYGMNL8OLFEDC/Slide07.jpg Congenital Cardiac Defects https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1423408126089-ME1I96PCWNAMT4FRPCC5/Slide10.jpg Congenital Cardiac Defects https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1423408131755-61LT59ZCEDN7XSHL4050/Slide14.jpg Congenital Cardiac Defects https://www.wythelab.com/avms-and-hht daily 0.75 2018-04-30 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521057960998-4C4BZG84DII8YLLMEBPJ/Slide08.jpeg AVMs and HHT https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521057563381-6H4P9HV2TJSJCE4YI55Q/Slide10.jpeg AVMs and HHT https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521057567864-ZFBETCTNARHHB9YZ89GF/Slide11.jpeg AVMs and HHT https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521058280414-IE0LZ5WWCT1K0YFL2KEC/THI_02-15-2018.jpg AVMs and HHT https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521057637530-L7GB2B5XS0U2BBSY00F4/Slide66.jpeg AVMs and HHT https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521057570906-8OUTK11SUOEMVTNP2I23/Slide12.jpeg AVMs and HHT https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521063393119-CFKPKSSMTXE8AA1Q8AN1/20170425_adult+brain_884_rec0000.jpg AVMs and HHT micro-CT image of an adult mouse brain following vascular perfusion of a contrast agent. 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https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521065039513-RPX1Z86VJO9OCQ01GCZ3/DB_Lab_Tour_2018.jpg Vascular Development https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1423406384854-1AM6CJSLY20PGVW07HCM/Slide05.jpg Vascular Development Images courtesy of Jason Fish's lab. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1423406369843-I32Y89PL90DVFVB6UCQX/Slide04.jpg Vascular Development https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1423406403536-BNSV1WG5A7HF7T6FLA1X/Slide45.jpg Vascular Development https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1440447043453-JC5KQN2RHJT9G4XJQW7H/Slide51.jpg Vascular Development From Fish JE, Wythe JD (2015) Dev. Dyn. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521059672439-X7UZ953QSMNVCO8QH2N4/Slide09.jpg Vascular Development https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521059679438-UG5YI8GZ8JOQOMBU37PW/Slide10.jpg Vascular Development https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521060386830-QQISVUDXDOKV4RSPQZJG/Slide11.jpg Vascular Development To understand the transcriptional regulation of early arteriogenesis, we chose to focus on the earliest known arterial marker, the gene Delta like 4, which encodes a ligand for the Notch family of receptors. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521059695045-332LV3ZM37B5V9G3LHZB/Slide12.jpg Vascular Development https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521059793698-U1YT7SXDMWYMWRV8C7WF/Slide13.jpg Vascular Development https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521059794026-TP527Q3JSJA0FL8XRDCR/Slide14.jpg Vascular Development https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521059794212-6VFTUGKMAS6430HELRCV/Slide15.jpg Vascular Development https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521059869956-08XO361BOZC562LLW10P/Slide17.jpg Vascular Development https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521060461966-CP86XQIV4E9VQ9QJW31X/Slide20.jpg Vascular Development https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521060335387-XLBQVACY0AGX1Z6C7D08/Slide06.jpg Vascular Development Interestingly, this same pathway seems to regulate some aspects of VEGF-induced gene expression during angiogenesis. See Fish JE et al., Development, 2017 for more. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1440507533296-GVTXKKCWVXZHJE2IQ6SI/Slide05.jpg Vascular Development We are also interested in nerve-vessel interactions, from alignment and patterning during development, to their cross-talk in disease settings. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521060129591-Q65011UX3YWKRX4A8JK1/Dll4-BAC_CD31-tuj1-betaGal-RGB.jpg Vascular Development Nerves and arteries align in the mouse forelimb skin. IHC for Dll4-BAC-nls-lacZ (arteries, blue) and CD31 (all endothelial cells, green) and Tuj1 (nerves, red). From Herman et al., 2018. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1440507642462-ZG1T0GCP7LVGI2BIUMO0/Slide38.jpg Vascular Development https://www.wythelab.com/tissue-clearing-resources daily 0.75 2025-07-16 https://www.wythelab.com/reporter-allele-choice daily 0.75 2020-11-04 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1454447267918-PI5XDXG58XUKJMXTEGPU/image-asset.jpeg Reporter Allele Choice Two hearts were isolated from embryos following crossing a transgenic Nxk2.5::Cre driver line to either A) a Rosa26-LSL-EYFP reporter (on the left) or B) a Rosa26-ai6 (zsGreen) reporter (on the right). https://www.wythelab.com/manuel-cantu-gutierrez daily 0.75 2024-08-03 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1464815692869-M0JJ3I5B57VR6FB4ZCV4/image-asset.jpeg Manuel Cantu Gutierrez https://www.wythelab.com/publications daily 0.75 2020-08-21 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1578667649771-YTQEMBQFL57TACJ94M1D/F1.medium.gif Publications https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1578668603799-XEPBSNI7ECGW9XWT0BED/nejmoa1709449.jpg Publications https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1578667665975-GE2B1FDEYL55NNO6PR3S/2020-Journal_of_Neuroscience_Research.jpg Publications https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1596483463899-S8L9SV7JKDU2P2OIK2Z0/JCI_insight_cover.png Publications https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1596482667951-4GV4H2N8FGTY789MZF5K/Circ_Res_Graphical_Abstract.png Publications https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1596481702756-HZFWQ6IKYJPX48SLDG9C/S1R1_JCI_Image-1.png Publications https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1589833243818-R5RSFL0WOYB3ZI4APPF7/image-asset.jpeg Publications https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1573164152210-KMJHJ8LJMD79R6AWGTR1/EHat7ecW4A0R_HD.jpg Publications https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1562094894336-H9UE6TLE3YJGCZG3GRH2/Slide2.jpeg Publications https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1562094148454-MUU0OB1PDGEE2FTDOHIK/Slide1.jpeg Publications https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1562095252708-33MB1822FDE88KCFQVID/Slide3.jpeg Publications https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1525106815841-X76DTEZM09G50JPFNVXN/fx1.jpg Publications https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521056910901-50WOFYX2ZCTF1XS3GOW5/2-17-17-Skin-IHC-Good.lif_14.5-skin-Dll4BAC-podo488-cd31594-bgal647-10X-1.5zoomSnapshot3_preview.jpg Publications https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1521056485244-Y5BRC28FHGRK3FVCXMQ5/THI_02-15-2018.jpg Publications https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1499779474863-YD1FOIU94VGSI039VO59/image-asset.png Publications https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1499777411689-DJM40J0KVJYTH633ULYU/F4.large.jpg Publications https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1499779150829-3F1IF0LWSBDDWKV86Y9J/image-asset.jpeg Publications https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1499778135514-95BZ8PLHN8FKAKQB76YT/image-asset.png Publications https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1499779524879-PUG7HSP2E4CUT5O1LYC4/651+A+mTmG+R%26G2.jpg Publications https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1499778830686-NFBZRWPTRO4TYBSJKYTS/image-asset.png Publications https://www.wythelab.com/carlos-p-flores-suarez daily 0.75 2024-08-03 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1535141391307-86USM74KHV8VJYR3GN85/Carlos_image_2.jpg Carlos P. Flores Suarez https://www.wythelab.com/new-page daily 0.75 2024-08-03 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1544537924499-ANODUJHVO6A7XPGJZA77/Figure+3C.png Wythe Lab - Databases https://www.wythelab.com/funding daily 0.75 2020-08-03 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1559942482533-B44SB9DPK32O78YLHLRZ/download-1.jpg Funding PR170168 / W81XWH-18-1-0350 (Wythe) https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1559943062522-AF8VLM4KJ50IG0GMYJYM/download.png Funding 1R01HL144775 (Lingappan) R01HD099026 (Dickinson) R01HL146745 (Mayerich) R01HL130129 (Chen) UG3HL151545 (Lagor, Bao, Suh) https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1559944287618-BHHRGI7Q97W3O5TCTAPN/download-1.png Funding 391385 (Wythe and Radovanovic) https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1596483748553-IA7HXUZWIPTIGU5BLGV2/CPRIT_logo.png Funding RP200402 (Wythe) https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1559942619216-5RNNKM8MDVIJZXJHMLSK/services.AmHeartLogo1_a0792b4a-5056-a348-3a5293804a0ff3ed.gif Funding 19POST34430008 (Herman) 19PRE34410104 (Cantu-Gutierrez) 16GRNT31330023 (Wythe) 12SDG12060353 (Wythe) https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1559942788733-AS6CW69Q9HW81APLAYW6/social-logo-baylor3.jpg Funding https://www.wythelab.com/williamson-turner daily 0.75 2024-08-03 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1562098161374-1XFSJZEB6P8DI5J2518S/williamson-turner-photo.png Williamson Turner https://www.wythelab.com/gabrielle-largoza daily 0.75 2024-05-24 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1603744982102-UDH3JWR267N96DCYQLRU/B_and_W_thumbnail_Largoza_Image_2.jpg Gabrielle Largoza https://www.wythelab.com/juan-cerda daily 0.75 2024-08-03 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1602788460460-JVQEXEWCEL7V4TI0C7GI/Juan_BandW.jpg Juan Cerda https://www.wythelab.com/publications-1 daily 0.75 2026-02-18 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1603990724062-SI6LGM9T0KHFNBFLJBGC/Picture1.png PUBLICATIONS https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1578667649771-YTQEMBQFL57TACJ94M1D/F1.medium.gif PUBLICATIONS https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1578668603799-XEPBSNI7ECGW9XWT0BED/nejmoa1709449.jpg PUBLICATIONS https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1578667665975-GE2B1FDEYL55NNO6PR3S/2020-Journal_of_Neuroscience_Research.jpg PUBLICATIONS https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1623230892900-7ZJ0KQA7FNX986XMNI07/front_matter_23-6-1.png PUBLICATIONS https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1596483463899-S8L9SV7JKDU2P2OIK2Z0/JCI_insight_cover.png PUBLICATIONS https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/0d6c40a6-a190-4f7f-8415-9b07d7e694cd/2026_Paper_Figures_Wu_et_al.jpg PUBLICATIONS - 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Lab dinner at Armadillo Palace, Summer 2022. Great team! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1649361045836-D2OEOLAXXA0T56JFGU1J/MicrosoftTeams-image+%281%29.png THE LAB - After the 2022 CVRI symposium, looking fancy! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1643495960782-9SX6PD4D10GFWOLNR9IE/IMG_9100.JPG THE LAB - Lab dinner at Hu's Cooking! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1648576175883-DDLL5MB4IB07ET63ZKTX/Armadillo_Palace_2022.png THE LAB https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1564436872513-00K071EEUL4AW0DHYTRU/IMG_7207+2.jpeg THE LAB Getting burgers together out at Hop Doddy in Rice Village, summer 2019. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1478818055966-LETSOHR99FXZGMGZFYEW/Ctj9FG3VYAEymmS.jpg THE LAB The team cranking away in the lab! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1535574460181-REB8UZIU6I3YT1QKJD1S/32709151_2099885273633954_1445678299547172864_o.jpg THE LAB Manuel walking folks through his poster at the annual CVRI symposium in 2017 at BCM. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1535574003697-ZGB4Z047XT1FM0T8QD3N/Image-3.jpg THE LAB Lab dinner at Hop Doddy to wish Abiud well back at college and to celebrate Carlos joining the lab. Alex Herman was missed! Summer 2018. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1466092960179-7URNET7I0UI44WSH56I1/IMG_2990.JPG THE LAB Taco Friday at "Many's taco truck" with the entire lab. (L-R) Manuel, Kesha, Alex, Karen, and Josh. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1573163133745-CMV4BUWMGYCSTZ56OKX8/EExKF85XkAQi1bZ.jpg THE LAB Giving a talk at the Smithville Campus of MD Anderson Cancer Center. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1478818124954-1950R9HJ3SG11OIL0N4G/Cu02-oJVMAABAS_.jpg THE LAB Giving a talk at the South West Regional SDB meeting at Salt Lake City, October, 2016. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1478818062022-IKLT15716FD9K8SW47A8/Cth7LmiVYAEk-X7.jpg THE LAB Manipulating embryos with my former graduate school classmate, George T. Eisenhoffer, in his lab across the street at MD Anderson Cancer Center. Go fish! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1453524923410-6UF0R2UEE92LCO00G3G4/CQZgtfKUkAALtIH.png THE LAB Giving a talk at the 2015 Southwest Society for Developmental Biology Regional Meeting. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1453496401115-GT6RCJD9Y1TIX269LY3Y/IMG_2588.jpg THE LAB Lab lunch at Torchy's Tacos! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1573162293292-S4B3ZO78WDATHT1Z8J7F/r_1-Group-Photo-2019-Scientific-Conference_cropped.jpg THE LAB 13th Cure HHT International Scientific Conference Photo. Josh is in there somewhere! An awesome meeting in Puerto Rico! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1573162391713-DK6WEVGQG9KLQABO8SNK/DLfl6P3UEAALU_3.jpg THE LAB A whole lotta University of Utah Alumni in one room at the Southwest Society for Developmental Biology 2017 meeting poster session. Houston did a great job hosting this awesome regional meeting! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1453496401204-MXPH4JGOIRD14NRNN3TT/IMG_1768.jpg THE LAB Holiday Lights in Houston. They look remarkably like vessels! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1573163382004-MOZO7632BHJ5TB62Q2NU/D6SdDcdWAAI6Bax.jpg THE LAB Talking at the 2019 Weinstein Cardiovascular Development and Regeneration Meeting in Indianapolis. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1481804613347-U8LCHQ1EXPHSX1HX0Q5T/Wythe+Lab+Christmas.png THE LAB https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1453496394851-2EH2VD0ZP0BTBT7EZKMN/IMG_610_jpg.jpg THE LAB Alex wins a blue ray player at the holiday raffle. https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1549384385341-4BQ4YDJ17M123ELC1UPV/IMG_1403.JPG THE LAB https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1643495905083-9TLWOH7M1K06728STBDB/FGhzNRbWUAAaesJ.jpg THE LAB - Celebrating Manuel's defense! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1643495914695-4HDG11ME9HLV3EASCPUS/FGhzNRcXoAEqQ5l.jpg THE LAB - Manuel's thesis defense cake! Gabrielle's got some hidden talents! https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/6c1fab81-c8f9-4b24-93cf-9e0d301c6e11/University_of_Virginia_School_of_Medicine.png THE LAB - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.wythelab.com/microscopy-resources-tissue-clearing-etc daily 0.75 2023-11-01 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1657825490125-XZUC22F2OQ3AOIXBGKT0/IB4+Brain+65X.jpg Microscopy Resources (Tissue Clearing, etc) (Copy) https://www.wythelab.com/wythe-lab-databases daily 0.75 2025-10-22 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1657825355670-XB18ZTZ7HW2Q0UD6I8DN/database-1024x703.jpg Wythe Lab Databases https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1544631590832-9WSK6S6T5BLR7NO29YPV/Figure+3C.png Wythe Lab Databases https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/d27cee0a-a1f8-4449-ae1d-2b5bcc44b097/Plasmids.jpg Wythe Lab Databases https://www.wythelab.com/glioma daily 0.75 2023-07-25 https://www.wythelab.com/ashley daily 0.75 2022-03-29 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/94c14301-4eca-4744-a462-b7b8c35837e9/Picture+3.jpg Ashley - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.wythelab.com/epigenetics-and-single-cell-data daily 0.75 2025-11-17 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/1657825106119-U0KUTBPKQ4SLKU4LR4JI/DNA_strand.jpg Wythe Lab Epigenetics And Single Cell Data https://www.wythelab.com/oscar-ruiz daily 0.75 2022-08-22 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/c6d30c96-ffe7-4406-a364-24a9e4d093f5/Oscar_Ruiz_BW.jpg Oscar Ruiz - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.wythelab.com/william-gillespie daily 0.75 2025-01-30 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/6c0aabdd-76fd-45f8-9358-7c92d4f3ac47/me.jpg William Gillespie https://www.wythelab.com/parker daily 0.75 2024-05-06 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/17054ee8-ea26-4557-b700-e37aaf4da50a/image+2.jpg Parker Chapman - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.wythelab.com/lili-mosser daily 0.75 2024-05-10 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/e2f2bcda-fd1e-4542-a97d-6a4a18e0bc16/IMG_1360.JPG Lili Mosser - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.wythelab.com/michelle-sherman daily 0.75 2024-05-15 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/42059fcc-5ebb-4ccc-8d18-bbd1b67e5a99/black+%26+white+photo.jpg Michelle Sherman - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.wythelab.com/natalie-lisenby daily 0.75 2025-01-30 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/63be8d33-4c9b-4375-aeb2-191118862937/1657492496203.jpg Natalie Lisenby - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.wythelab.com/azeez-ishola daily 0.75 2025-06-12 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/3619d008-59f3-46c2-bbe3-15514e635ca9/PXL_20230806_220550540.jpg Azeez Ishola - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.wythelab.com/athira-pillai daily 0.75 2025-01-30 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/858b87db-8d20-409e-b7c8-f769bfa0ea0b/IMG_0260.jpg Athira Pillai https://www.wythelab.com/jaden-singh daily 0.75 2025-06-12 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/60eb7728-82b6-4eda-9c62-9049500e0856/DSC00472.JPG Jaden Singh https://www.wythelab.com/brenda-lu daily 0.75 2025-06-12 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/c5b3ee7b-65db-430b-8e10-fb106885f80a/Brenda+Lab+Bio+Pic+-+Black+%26+White.jpg Brenda Lu - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.wythelab.com/mengistu-shukare daily 0.75 2025-06-12 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/24fb5e70-9907-4a8a-8662-876abc674f8f/022625-_-Dr.-Shukare.png Mengistu Shukare, PhD https://www.wythelab.com/kandace-moore daily 0.75 2025-06-16 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/a9070c3c-37c2-4041-a5c0-e5de2283b82e/IMG_4843.jpg Kandace M. Moore https://www.wythelab.com/karen-lin daily 0.75 2025-06-16 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/86a42d0c-b498-41cb-8c4c-ead5f0f710ab/Lin_Karen_Photo_BW.jpg Karen Lin https://www.wythelab.com/anika-singh daily 0.75 2025-06-18 https://images.squarespace-cdn.com/content/v1/542b27b6e4b04193388466d4/9999f7cf-0608-4fe6-bbca-d50026ccf5ae/1011525077+%281%29.jpg Anika Singh