Wythe Lab Epigenetic and Transcriptional Data
Cantu Gutierrez M., and Hill M., et al., Nature Cardiovascular Resarch, 2025
BigWig Tracks at UCSC Browser for ATAC-seq from E12.5, P7, and adult Murine Brain, Heart, Lung, Kidney, Liver, and Heart (whole organ input and Endothelial Cells)
BigWig Tracks at UCSC Browser for Omni-ATAC-seq from Human Brain Microvascular Endothelial Cells
Single Cell Mouse Brain Data (E9.5-Adult): https://wythelab.shinyapps.io/ScRNA_Brain_EC_Development/
Broad single cell explorer (E9.5-Adult Brain ECs): https://singlecell.broadinstitute.org/single_cell/study/SCP1922/defining-the-transcriptional-and-epigenetic-basis-of-organotypic-endothelial-diversity-in-the-developing-and-adult-mouse
Rstudio Object: https://doi.org/10.6084/m9.figshare.28266635
Mouse bulk ATAC-seq, RNA-seq data, and brain scRNA-seq data Gene Expression Omnibus (GEO) accession #: GSE185345
Human brain EC omni-ATAC-seq data Gene Expression Omnibus (GEO) accession #: GSE187565
Carlson J.C., and Cantu Gutierrez M.E., et al., Neuro Oncology, 2021
scRNA-seq from bulk murine tumor and enriched endothelial cells, as well as bulk RNA-seq from Tumor Derived Lymphatic Endothelial Cells (TDLECs), Tumor Associated Vessels (TAVs), Tumor Derived Endothelial Cells (TDECs), and bulk tumor: GEO GSE158700
Shao Y. et al., Genes and Development, 2021
ATAC-seq data from the E12.5, P6, and adult mouse brain (bulk): GEO GSE152719
Fish J.E., Suarez Flores C.P., Boudreau E., et al., Circulation Research, 2020
RNA-seq from empty vector and pCS2-KRAS4A-G12V transfected HUVEC treated with U0126 (MEKi), LY294002 (PI3Ki) or DMSO (vehicle): GEO GSE150426