FEATURED PUBLICATIONS
For a complete list of publications, please click here.
2020
Fish JE, Flores-Suarez CP, Boudreau E, Herman AM, Gutierrez MC, Gustafson D, DiStefano PV, Cui M, Chen Z, Berman De Ruiz K, Schexnayder TS, Ward CS, Radovanovic I, Wythe JD. Somatic Gain of KRAS Function in the Endothelium is Sufficient to Cause Vascular Malformations that Require MEK but not PI3K Signaling. Circulation Research, 2020. PMID: 32552404
Geng X, Yanagida K, Akwii RG, Choi D, Chen L, Ho Y, Cha B, Mahamud MR, Berman de Ruiz K, Ichise H, Chen H, Wythe JD, Mikelis CM, Hla T, Srinivasan RS. S1PR1 Regulates the Quiescence of Lymphatic Vessels by Inhibiting Laminar Shear Stress-dependent VEGF-C Signaling. JCI Insight, 2020. PMID: 32544090.
Vila Ellis L, Cain MP, Hutchison V, Flodby P, Crandall ED, Borok Z, Zhou B, Ostrin EJ, Wythe JD, Chen J. Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung. Developmental Cell, 2020. PMID: 32059772.
Hong SH, Herman AM, Stephenson JM, Wu T, Bahadur AN, Burns AR, Marrelli SP, Wythe JD. Development of barium-based low viscosity contrast agents for micro CT vascular casting: Application to 3D visualization of the adult mouse cerebrovasculature. J Neurosci Res. 2020. PMID: 31630455
2019
Cantu Gutierrez A, Cantu Gutierrez M, Rhyner AM, Ruiz OE, Eisenhoffer GT, Wythe JD. FishNET: An automated relational database for zebrafish colony management. PLoS Biology, 2019. PMID: 31220074
Hill MC, Kadow ZA, Li L, Tran TT, Wythe JD, Martin JF. A cellular atlas of Pitx2-dependent cardiac development. Development, 2019.
PMID: 31201182.
2018
Wang K, Zhao S, Liu B, Zhang Q, Li Y, Liu J, Shen Y, Ding X, Lin J, Wu Y, Yan Z, Chen J, Li X, Song X, Niu Y, Liu J, Chen W, Ming Y, Du R, Chen C, Long B, Zhang Y, Tong X, Zhang S, Posey JE, Zhang B, Wu Z, Wythe JD, Liu P, Lupski JR, Yang X, Wu N. Perturbations of BMP/TGF-B and VEGF/VEGFR signaling pathways in non-syndromic sporadic brain arteriovenous malformations (BAVM). Journal of Medical Genetics, 2018. PMID: 30120215
Xiao Y, Hill MC, Zhang M, Martin TJ, Morikawa Y, Moise AR, Wythe JD, Martin JF. Hippo Signaling Plays an Essential Role in Cell State Transitions during Cardiac Fibroblast Development. Developmental Cell, 2018. PMID: 29689192.
Herman AM, Rhyner AM, Devine WP, Marrelli SP, Bruneau BG, Wythe JD. A novel reporter allele for monitoring Dll4 expression within the embryonic and adult mouse. Biology Open. 2018. PMID: 29437553.
Nikolaev SI, Vetiska S, Bonilla X, Boudreau E, Jauhiainen S, Rezai Jahromi B, Khyzha N, DiStefano PV, Suutarinen S, Kiehl TR, Mendes Pereira V, Herman AM, Krings T, Andrade-Barazarte H, Tung T, Valiante T, Zadeh G, Tymianski M1, Rauramaa T, Ylä-Herttuala S, Wythe JD, Antonarakis SE, Frösen J, Fish JE, Radovanovic I. Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain. New England Journal of Medicine. 2018; 378(3):250-261. PMID: 29298116.
2017
Fish JE, Cantu Gutierrez M, Dang LT, Khyzha N, Chen Z, Veitch S, Cheng HS, Khor M, Antounians L, Njock MS, Boudreau E, Herman AM, Rhyner AM, Ruiz OE, Eisenhoffer GT, Medina-Rivera A, Wilson MD, Wythe JD. Dynamic Regulation Of VEGF-Inducible Genes By An ERK/ERG/P300 Transcriptional Network. Development. 2017; 144(13):2428-2444. PMID: 28536097
2016
Wang J, Xiao Y, Hsu CW, Martinez-Traverso IM, Zhang M, Bai Y, Ishii M, Maxson RE, Olson EN, Dickinson ME, Wythe JD, Martin JF. Yap and Taz play a crucial role in neural crest-derived craniofacial development. Development. 2016; 143(3):504-15. PMID: 26718006
2015
Lizama CO, Hawkins JS, Schmitt CE, Bos FL, Zape JP, Cautivo KM, Borges Pinto H, Rhyner AM, Yu H, Donohoe ME, Wythe JD, Zovein A. Repression of arterial genes in hemogenic endothelium is sufficient for haematopoietic fate acquisition. Nat Commun. 2015; 6:7739. PMID: 26204127
Fish JE, Wythe JD. The molecular regulation of arteriovenous specification and maintenance. Dev Dyn. 2015; 244(3):391-409. PMID: 25641373
2014
Devine WP, Wythe JD, George M, Koshiba-Takeuchi K, Bruneau BG. Early patterning and specification of cardiac progenitors in gastrulating mesoderm. Elife. 2014. PMID: 25296024
2013
Wythe JD, Dang LT, Devine WP, Boudreau E, Artap ST, He D, Schachterle W, Stainier DY, Oettgen P, Black BL, Bruneau BG, Fish JE. ETS factors regulate Vegf-dependent arterial specificationt. Dev Cell. 2013; 26(1):45-58. PMID: 23830865